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The Pulmolines cohort is the overarching cohort structure of the Groningen Research Institute for Asthma and COPD (GRIAC). The mission of GRIAC is the multidisciplinary translational study of obstructive airway and pulmonary diseases and healthy ageing.
Patients with asthma, COPD and other lung diseases and their controls with normal lung function. The number of participants varies per subcohort and mounts altogether to more than 2.000 participants.
Data include sex and age, clinical diagnosis, lung function, smoking information, and variable: BMI, allergies, medication use, pathology diagnosis, CT-scans, comorbidity, genetics/genomics, epigenomics, expression- and proteomics data.
Asthma and COPD are highly prevalent in the general population, and thus focusing on these two disease areas is appropriate and has a high societal relevance. Research within GRIAC is ranging from cellular models to the underlying disease models to the clinic (translational research) with transdisciplinarity as a major feature and an overarching emphasis on healthy ageing and (personalized) diagnosis and drug development. Recognizing early disease features and relevant etiologic factors contribute to options for prevention. Societal impact therefore comprises prevention as well as aiming to provide (personalized) solutions if disease is present. Recent results are highlighted in the GRIAC Annual Report.
University Medical Center Groningen (UMCG)
PO Box 30.001
9700 RB Groningen
University Medical Center Groningen
Groningen Research Institute for Asthma and COPD (GRIAC)
9713 GZ Groningen
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