Clinical Pharmacy and Pharmacology

Clinical Pharmacy and Pharmacology

Personalised medicine and targeted therapy Department
Personalised medicine and targeted therapy
We study variability in drug response and the underlying molecular mechanisms as well as the biological, clinical, behavioral and environmental characteristics influencing response variability. This should lead to more personalised and targeted therapy with better outcomes for individual patients as well as more cost-effective treatment for society.

We search for new treatment targets and approaches to optimise the use of drug treatments in individual patients. We want to better understand variability in drug response and underlying molecular mechanisms, in particular related to the treatment areas of diabetes and oncology. We work on new techniques for drug development, drug exposure monitoring, molecular imaging, biomarker use, and we test interventions to improve drug use and treatment decisions in clinical practice. In this way, we want to improve outcomes for individual patients and increase the cost-effectiveness of medication treatment for society.

Our research lines include:

  • preclinical pharmacological research;
  • drug development, molecular imaging and drug monitoring;
  • clinical trials, biomarkers, individual drug response and patient-relevant outcomes;
  • drug utilisation, pharmaceutical services and regulatory science.
Relevance

How our research benefits to society

Drug therapy is the cornerstone for treating many diseases and preventing disease progression and complications. In our department, we conduct pre-clinical, translational and clinical research, with a special focus on diabetes or cancer. In recent years, we have made important discoveries to prevent the progression of diabetic kidney disease, which may affect up to a third of all people with type 2 diabetes. Furthermore, our department is involved in the development of innovative diagnostics and treatments for cancer. In addition, we are testing a range of new strategies to support optimal and cost-effective drug use in individual patients in clinical practice.

Contact

University Medical Center Groningen (UMCG)
Department of Clinical Pharmacy and Pharmacology
PO Box 30.001
9700 RB Groningen
The Netherlands

Visiting address
University Medical Center Groningen (UMCG)
Department of Clinical Pharmacy and Pharmacology
Hanzeplein 1
9713 GZ Groningen