Research building banner

MoHAD: Mechanisms of Health, ​Ageing and Disease

Bridging Fundamental Biology to Breakthroughs in Health, Ageing, and Disease Interventions. Institute
Bridging Fundamental Biology to Breakthroughs in Health, Ageing, and Disease Interventions.
We envision a future where our research on molecular and cellular mechanisms enables discoveries and development of basic biology, targeted diagnostics, personalized treatments, and innovative preventive strategies.​

Our mission is to foster knowledge on the mechanisms underlying health, ageing and disease, and promote collaboration among fundamental, translational, and clinical researchers. Our long-term goal is to exploit a deeper understanding of molecular and cellular mechanisms for the development of innovative therapeutic applications aimed at preventing multiple morbidities and extending healthy longevity.

Research themes

  • Mechanistic and translational aspects of initiation, diagnosis and treatment of cancer;
  • Cardiovascular and metabolic disease and treatment;
  • Mechanisms of ageing and age-related diseases.
Relevance

How our research benefits to society

In the Netherlands and worldwide, life expectancy significantly increased in the last 50 years. A major societal challange is that an aging population is significantly more likely to develop multiple morbidities. Individuals with multiple morbidities have an decreased quality of life, and the costs of care for the elderlies are extremely high. A better understanding of the underlying causes of aging and disease offers a tremendous opportunity to develop clinical applications that can improve life quality and reduce healthcare costs.

Research programmes