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Although in the early stages, loss of kidney function can be mild and asymptomatic, advanced stages are associated with numerous adverse health outcomes. These include burdensome kidney replacement therapies, cardiovascular disease, reduced life expectancy, and decreased quality of life. To tackle this issue, the GKC programme promotes interventions related to the prevention and treatment of kidney function decline, with a focus on personalized medicine and cardiorenal interaction. The GKC research activities range from basic science and experimental and clinical intervention studies to the clinical implementation and dissemination into clinical practice and society. The GKC programme includes:
Lifestyle factors contributing to accelerated ageing, such as nutrition, obesity, lack of physical activity, and environmental toxins, decrease the quality of life and reduce the life expectancy of patients with kidney disease. The GKC longitudinal, lifelong approach enables the researchers to generate data, resources, and concepts that promote therapeutic interventions. These improve the health outcomes, life expectancy, and quality of life of patients with chronic kidney disease and, therefore, contribute to healthy ageing.
The multidepartmental collaboration with the Division of Nephrology and the departments of Pathology and Medical Biology and Clinical Pharmacy and Pharmacology enables our researchers to develop innovative translational research approaches. Because the GKC researchers have access to the rich scientific resources available in the clinic and the research facilities, they are able to provide more insight into loss of kidney function and into effective treatment and prevention strategies. The efforts include:
University Medical Center Groningen (UMCG)
Institute GUIDE
GKC
P.O. Box 196
9700 AD Groningen
The Netherlands