Immunolines

Data and biobank for the onset and treatment of (auto)immune diseases Cohort

Data and biobank for the onset and treatment of (auto)immune diseases

ImmunoLines is a collaborative effort of clinical and research departments. The ImmunoLines data and biobank enables researchers to conduct comprehensive studies aimed at increasing understanding of the onset and treatment of (auto)immune diseases.

ImmunoLines supports translational research into immune-mediated inflammatory diseases (IMIDs), both within UMCG and in collaboration with external partners. Our cohorts are designed to elucidate the mechanisms underlying (auto)immune diseases, focusing on the diversity in clinical presentation, severity, affected organs, and underlying immunopathogenic pathways.

By advancing our knowledge of these mechanisms, ImmunoLines aims to facilitate earlier recognition of disease and to improve patient outcomes through more targeted, mechanism-based interventions.

Our aims

Clinical and translational research within ImmunoLines aims to:
promote early recognition of (auto)immune diseases;
enable translation of insights across (auto)immune diseases;
facilitate the development of personalized care and targeted therapies.

- Patients with (auto)immune diseases
-   Systemic Lupus Erythematosus and Systemic sclerosis
-   Sjögren Expertise Centre
-   Vasculitis Expertise Center
-   The Groningen Leeuwarden Axiale Spondylartritis (GLAS)

See also: research groups of the UMCG research department Rheumatology and Clinical Immunology
- Clinical data
- Patient-reported outcome measures (PROMs)
- Biological samples
Detailed information on available data and samples can be found in the UMCG Research Data Catalogue:
- IMMUNOLINES - RESULT | UMCG Data catalogue
- IMMUNOLINES - SLE - DAiRE | UMCG Data catalogue
- IMMUNOLINES - GLAS | UMCG Data catalogue
- UMCG department Rheumatology and Clinical Immunology
- Sjögren Expertise Centre
- Vasculitis Expertise Center
- Groningen Leeuwarden Axiale Spondyloarthritis (GLAS) cohort
For more details about participation, visit the Immunolines webpage (in Dutch).

Relevance

How Immunolines benefits to society

The University Medical Center Groningen (UMCG) is dedicated to promoting healthy ageing. For healthy ageing within (auto)immune diseases, early identification of patients – before irreversible organ damage occurs – is critical. The ImmunoLines data and biobank is fully aligned with the FAIR principles (Findable, Accessible, Interoperable, and Reusable). This unique resource is ideally suited for international collaboration and securing external research funding. ImmunoLines is embedded in PRECISION – Personalized medicine Research Institute Groningen and TRIGR – Translational Immunology Groningen (TRIGR). TRIGR focuses on unraveling the pathophysiological mechanisms of immune-mediated chronic diseases and provides a strong platform for translational immunology research.

We welcome patients into our care and actively invite them to participate as partners in our cohort research. Together, we aim to jointly identify and develop optimal, personalized treatment strategies.