Samples will be collected prior to the start of treatment, as soon as possible after presentation. A deferred proxy consent procedure is in place to allow the collection of data and biomaterials before having obtained written consent. Clinical data, imaging data and biomaterials (blood, urine, faeces, and hair) will be collected. The digital infrastructure used ensures the automated capturing of all bedside monitoring data (vital parameters and electrophysiological waveforms), and the secure import of data from other sources, such as the electronic health records drawn up by the hospital staff, ambulance staff, general practitioner, the municipal registration, and the pharmacy.
- reason for admission, including signs and symptoms;
- physical examination and vital parameters (e.g. body temperature, blood pressure, heart rate, breathing frequency);
- general characteristics (e.g. judgment of treating physician);
- additional results (e.g. X-ray images, scans, ultrasound scans, laboratory test results);
- pharmacologic and non-pharmacologic treatment.
- demographic data (e.g. age, sex, marital status, education, living situation, ethnicity);
- family history;
- lifestyle (e.g. smoking, alcohol consumption, illicit drug use);
- global functioning and experienced health (e.g. EQ-5D-5L, Katz-15 scale, Piper Fatigue Scale-12, PHQ-15);
- mood (e.g. PHQ-2, PHQ-9, GDS-15);
- shared decision-making (e.g. PSQ-18, OPT);
- nutrition and activity (e.g. SNAQ, MUST, SQUASH);
- frailty, delirium and cognitive functioning (e.g. VMS frail older patients, 4-AT, 6-CIT).
- citrate plasma;
- EDTA plasma + buffy coat (DNA);
- heparin plasma;
- whole blood (PAXgene RNA extraction);
- lock of hair.