Depression affects nearly one in five people during their lifetime. Despite available therapies, 20–30% of patients do not recover with standard treatment and develop treatment-resistant depression. In the Netherlands alone, depression leads to approximately €1.6 billion in direct healthcare costs and €1.8 billion in lost productivity each year.
INDEPTH aims to close the gap between research and care by facilitating the development, validation and implementation of innovative treatment strategies. These include both pharmacological and non-pharmacological therapies, as well as advanced clinical decision-making tools that use neurobiological insights, data science, and artificial intelligence.
The program is coordinated by University Medical Centre Groningen and involves key stakeholders, such as GGZ inGeest, Pro Persona and Parnassia Groep. It builds on already existing data-infrastructure collaboration in the Netherlands Network for Difficult-to-Treat Depression and is supported by the nationwide clinical network DepressieNet.
The INDEPTH PPP program is made possible via the Public-Private Partnership (PPP) subsidy scheme introduced by the Top Consortium for Knowledge and Innovation - Life Sciences & Health (TKI-LSH aka Health~Holland). Through the program, parties can apply for PPP projects with the PPP subsidy from Health~Holland.
An amount of 4 million Euros PPP subsidy has been allocated to the INDEPTH Program to distribute among and support collaborative projects by issuing a Call for projects to run between 2026 and 2031. Below you find additional information about the INDEPTH program consortium and the funding scheme. For additional information, please reach out to [email protected]
The Program is part of the Health Holland PPP subsidy scheme which aims to develop partnerships with industry, by issuing a Call for projects, allocate resources, and oversee their implementation. The program welcomes applications for collaborative projects of healthcare institutes and companies focused on applied research on treatment-resistant depression within two domains:
Project ideas will be evaluated on academic and societal impact as well as on the more direct economic impact.
Through the INDEPTH program, consortia have the opportunity to jointly apply for PPP projects. Proposals are assessed in two stages. A pre-application is mandatory to be considered for next phase. Pre-applications can be submitted at any time. The indicated application templates are mandatory to use.
If selected for the full application phase, the applicant will receive further instructions regarding the documents for the next phase. When submitting to the full application phase, only minimal changes on project scope, partners and budget (max. 20% deviation) are allowed. Introduced changes should be notified to the Program Group for approval.
After assessment, the INDEPTH Program Group strives to communicate about the selected pre-proposals around 21 August 2026 and about the awarded full proposals around 15 January 2027.
Upcoming online information sessions:
To register, please reach out at [email protected]
For the pre-application phase, it is required to submit:
For the full application phase, it is required to submit:
For the finalization of the project dossier, selected full proposals will also have to provide:
Documents and templates to download for the INDEPTH pre-application phase:
We strongly advice to have a look also at the following documents to become aware and acquainted of the framework for public-private collaborations set out for this program.
Documents and templates for consultation and for full submission phase:
For submitting the application and more information on the procedures and requirements, please contact [email protected]
