The research mission of the section Molecular Neurobiology is to study the molecular and cellular processes and overall function of the central nervous system (CNS) during development, healthy ageing and CNS diseases. Through state of the art techniques and approaches we aim to identify novel targets to promote healthy aging, to delineate disease aetiology and to modulate progression.
In the context of the central theme Healthy Ageing of the University of Groningen, the interrelated fields of interest of the section are neurophysiology and neuroimmunology. CNS ageing and inflammatory neurodegeneration are central topics. These processes are mainly studied in the context of neurodegenerative diseases like Alzheimer’s disease and multiple sclerosis (MS):
Our research impacts our society by the potential development and identification of novel intervention strategies to treat diseases that affect the human CNS by increasing our fundamental knowledge of the underlying neurobiological processes.
Environmental factors in combination with hereditary or acquired gene mutations can lead to severe human CNS pathologies. The interaction between these environmental factors and the genetic risk conveyed by these gene mutations is not always known, and their causality to CNS disease is poorly understood. Unveiling their effect on molecular, cellular and CNS tissue functions and physiology is essential to identify potential targets and to develop therapeutic interventions:
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