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Mindlines

Mindlines

A real-world cohort of patients within secondary psychiatric care. Cohort
A real-world cohort of patients within secondary psychiatric care.
The UMCG University Center of Psychiatry fosters a strong collaboration with mental health organizations in the Northern Netherlands.

This partnership is called the Rob Giel Research Centre. Research within the RGOc is organized within three clinical networks (mood-disorders (MOPHAR), psychosis (PHAMOUS) and elderly geriatric psychiatry (ROM-GPS)) that bring clinicians, researchers and patients together. Within these networks, research questions are formulated, and new interventions are studied.

Each network collects clinical monitoring data into a large database, which can be enriched with health-insurance data and our care-consumption database. This way, a unique and very extensive data source is available for research within each network. 

Mindlines aims to:

  • develop tools to support personalised care by using predictive modelling based on individualized staging and profiling of patients, both within and across diagnostic categories; 
  • develop strategies to compensate for the individual deficits in treatment-resistant patients that hamper functioning; 
  • enable researchers with a broad range of research questions to study their topics of interest using a large database; 
  • enable an easy selection of patients for add-on studies. 

  • The overarching inclusion criteria of Mindlines include: 

    • age > 18 years; 
    • psychiatric diagnosis; 
    • receiving secondary care.

    Currently, data of around 20.000 patients have been included.  



  • The Routine Outcome Monitoring cohorts started with a focus on somatic on monitoring of psychotropic medication and their concurrent side effects. The scope has widened and the cohort now includes information on:

    • demographic characteristics;
    • diagnosis and medication use;
    • basic somatic measures;
    • routine blood screening results (metabolic status, vitamins, inflammation, etc.);
    • cognition;
    • life style;
    • frailty;
    • life events ant trauma;
    • functional and personal recovery;
    • social context.

    In a subsample, blood samples have been collected for whole genome sequencing.

    Please visit the UMCG Research Data Catalogue for more detailed information on our data and samples. 



  • Please visit Cliëntenparticipatie RGOc for more information about participation. 


  • Publications MOPHAR Drenthe (PUBMED) 


Relevance

How Mindlines benefits to society

The high prevalence of psychiatric disorders and their high disease burden call for innovative diagnostic and treatment strategies, that can only be realized when working together.  Mindlines data is clinical care data that is directly used in the treatment of patients. Most of the research questions are based on clinical practice and results are implemented in clinical care, thus patients directly benefit from the results from Mindlines.  

Contact

Edith Liemburg Researcher

University Medical Center Groningen (UMCG)
Mindlines
PO Box 30.001
9700 RB Groningen
The Netherlands

Visiting address
University Medical Center Groningen (UMCG)
University Center of Psychiatry 
Hanzeplein 1, Triadegebouw
9713 GZ Groningen

More information visite our website