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We aim to understand the role of host-microbe-environment interactions in human health and diseases by harnessing state-of-the-art biotechnologies and bioinformatics. Our interdisciplinary research encompasses the fields of genetics, microbiome, epidemiology, bioinformatics, computational and molecular biology.

Most of chronic diseases are complex diseases that are the result of the interactions of genetics, microbiome and environment. Moreover, in the concept of systems medicine, studying disease aetiology needs to take the systems of the human body as an integrated whole.

The research group has several research focuses:

  1. Identifying various risk factors that underlying an individual’s susceptibilities to develop complex diseases
  2. Employing machine learning techniques to stratify individuals for their disease risk and therapeutic response
  3. Generating genomics-based knowledge to support the development of personalized medicine
  4. Unlocking the potential of the gut microbiome in disease prevention and treatment
  5. Developing human based, personalized in-vitro model using hiPSC-based organ-on-a-chip technology for drug testing and disease modelling
Relevance

Pave the path towards a healthier and more sustainable society

  1. Promoting healthy ageing
  2. Innovative approaches (e.g., microbiome-targeted) for treatment and prevention
  3. Reducing the usage of animal models in biomedical research
  4. Increasing public awareness on the importance of the gut microbiome in human health

Contact

UMCG
Department of Genetics
Postbus 30.001
9700 RB Groningen
The Netherlands

Visiting address
University Medical Centre Groningen
Medical Faculty building (building 3211), 5th floor
Antonius Deusinglaan 1
9713 AV Groningen, The Netherlands