Our goal is to comprehend how aging impacts physical activity, mobility and task performance throughout life. We employ smart technologies and innovative interventions to assist people in maintaining health and independence for as long as possible. Our research highlights the crucial role of physical activity in disease prevention, cognitive health, and overall well-being throughout one's lifetime.

We examine movement, physical activity, and strategies in controlled laboratory and clinical settings as well as in real-life environments. Our work bridges various theoretical frameworks and methods—from computational neuro-biomechanical modeling, dynamical systems theory, and data science approaches to behavioral studies and observations of activities in everyday environments.

We aim to gain insights into motor, brain, and cognitive functions in physiological aging and neurodegenerative disorders. We also seek to understand the neuromechanical changes underlying adaptation, particularly in aging and age-related neuro-musculoskeletal disorders. We contribute to understanding the underlying factors of lifestyle-related diseases and physical inactivity, aiming to prevent them. Additionally, we explore ways to optimize the quality of our everyday movements, potentially leading to more healthy years.

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How our research benefits to society

Topics of our research program:

  • Age-related diseases and conditions, which are often lifestyle-related, are increasingly prevalent in society. With our research, we aim to increase the understanding of factors underlying active and healthy aging in populations of different backgrounds. Limited evidence exists regarding strategies supporting maintenance and adoption of (physical) activity and health behaviors. We study the mechanisms, processes and value of such strategies, implemented in real-life settings, such as health care or community settings. These include (lifestyle) interventions and (wearable) technologies and AI based decision support systems which provide real-time feedback or encouragement about health.

    Example projects:

    • Healthy living as a service: Realizing a sustainable and healthy society by improving Lifestyle and Social and Living Environment (HLaS)
      This transdisciplinary project brings together scientists – human movement sciences, art, architecture and urbanism, behavioral sciences, product design, and artificial intelligence – and engages citizens as local experts and partner companies. Supported by smart technology and AI-based decision support, the primary goal is to guide people towards healthier choices and sustainable lifestyle improvements by addressing both personal factors and environmental influences – including work, home, and surroundings.

      Project leader: Claudine Lamoth (funded by NOW KIC- Lifestyle and Living Environment

      Healthy Living as a Service - Gezondheid, Welzijn en Technologie (Dutch)
    • EmpoweRIng Citizens to adopt Healthy lifestyle Habits: A data-enaBled communIty-based ciTizen Science approach (ENRICH-HABITS)
      To empower citizens and communities to adopt and maintain healthier diet and physical inactivity habits, this project uses a holistic, social-ecological approach. Epidemiological and spatial data and citizen science are used to identify risk profiles and to co-create innovative and sustainable solutions with relevant stakeholders in the Netherlands, Denmark and Latvia.

      Project leader: Erja Portegijs, (Era4Health, EU-funded)

      EnRICH-HABITS
  • Physical activity, movement, behaviour and the living environment are closely intertwined. Adequate physical activity and the fostering of motor skills throughout life form an essential foundation for healthy aging. Everyday environments (i.e. play areas, workplaces, homes, green spaces, neighborhoods) play a crucial role in this process—they can either act as barriers or facilitators to being physically active. How do people adapt their actions to the environment across the timescales of performance, learning and aging? How do people perceive and act upon the possibilities for acting in their living environment? To answer these questions, we conduct field research in real-world settings, investigating -among other things-, the benefits of green exercise for elderly, which jumping stone configurations are most attractive, how the layout of a living environment affects the daily lives of citizens.

    Example projects:

    • Improving patient mobility and activity with the “Beweegziekenhuis” Toolbox
      This project aims to systematically implement and evaluate the "Beweegziekenhuis" toolbox across multiple hospital departments at the UMCG to encourage mobility and activity among patients and reduce the negative effects of prolonged bedrest. Using wearable sensors, behavioral mapping, and focus groups, the study will assess how feasible, acceptable, and effective the toolbox is in changing care practices and patient behavior. The findings will guide sustainable implementation of movement-promoting strategies into routine hospital care.

      Project leader: Nienke De Vries
    • Redesigning Chairs to Promote Postural Diversity and Movement
      Both adults and children spend increasing amounts of time seated during the day, which poses health risks. To promote more active sitting, this project examines build environments and objects that avoid trapping users in static postures, as conventional chairs typically do. Innovative designs, such as RAAAF’s ”The End of Sitting” and Lentala’s ROM and LUPA, support multiple work postures. These designs are also expected to naturally elicit changes between postures, helping to interrupt prolonged sitting in a single posture. This project investigates how adults and children use and experience these active designs in real-world settings, such as offices and classrooms.

      Project leader: Simone Caljouw
  • Our neuromechanical approach combines neurophysiology and biomechanics to study physiological aging and age-related disease. Concepts and tools from dynamical systems theory are applied to examine the stability and adaptability of movement patterns, particularly gait. Our research spans from healthy aging, to pathological conditions (e.g., osteoarthritis, sarcopenia), and from upper limb movements to altered gait and physical activity. These approaches help us understand changes in the neuromusculoskeletal system that underlie altered movement patterns, strength, and performance. This new knowledge serves as evidence for novel treatments that improve people's quality of life or help manage pathological conditions. Supporting technology includes gaming, virtual reality, and wearable devices for monitoring, diagnosis, and intervention.

    Example projects:

    • Neuromechanics of elbow replacement
      Joint arthroplasty is an effective treatment to replace a joint affected by osteoarthritis or rheumatoid arthritis with a prosthetic implant. In this project we collaborate with the department of orthopedics to study the loads in an elbow joint implant. Through this knowledge we aim to improve the loading guidelines that surgeons give to the patients concerning the implant and to ultimately extend the life of the implant.

      Project leader: A. Murgia
    • Gait adaptations over the life span
      Human walking is remarkably adaptable. We navigate diverse environments—avoiding obstacles and responding to unexpected situations—often while multitasking. Our research explores how aging affects this adaptability and at what cost. We conduct controlled lab studies using split-belt treadmills to examine neuromotor control across ages 18-85, and virtual reality environments to understand the dependency on visual information during walking. Additionally, we deploy wearable sensors to collect real-world movement data 24/7. Using machine learning and explainable AI, we predict mobility outcomes, assess fall risks, and evaluate frailty based on dynamic walking characteristics.

      Project leader: Claudine Lamoth
  • Physiological ageing and neurodegenerative disorders impact the structure and function of the central nervous system. A good understanding of the role of the central nervous system and the impact of changes therein on motor and cognitive function is crucial. In the Healthy Ageing Research Group, we adopt various imaging techniques (fNIRS, EEG) to study brain activity, connectivity and the interactions between the brain and muscles in the context of motor control, learning, memory and other cognitive functions. For example, we study if and how changes in brain activity and connectivity mediate the effects of physical activity on executive function.

    • Parkinson Vibrating Sock
      In this project, we study how sensory systems can be exploited to manipulate brain plasticity in the context of Freezing of Gait. With mobile brain imaging, we examine whether vibrations of the foot sole during walking positively affect brain activity and brain-muscle connectivity to ameliorate walking performance. The acquired knowledge can support the design of interventions aimed at improving cognitive and motor function in physiological ageing and neurodegenerative disorders.

      Project Leader: Menno Veldman (InterReg - EU financed)

      Parkinson Vibrating Socks
    • Personalized exercise for dementia
      Inactivity in an important risk factor for dementia. Physical activity interventions are offered to reduce the risk of dementia and to enhance cognitive and physical functions. However, adherence and effects are lower in people with dementia compared to their healthy peers. Therefore, a personalized approach is recommended. In this project we develop a fully digitalized tool to give personalized exercise recommendations to people with dementia. We follow a design-thinking approach and incorporate a wide range of factors affecting physical activity behavior of people with dementia classified in accordance with a socio-ecological model. The tool aims on use in both research and broader implementation within the general population.

      Project leader: Marieke van Heuvelen

Contact

C.J.C. Lamoth
Claudine Lamoth Professor of Movement Analysis and Smart technology in Aging

Department of Human Movement Sciences
Internal postcode FA23
PO Box 998
9700 AZ Groningen
The Netherlands

Visiting address
Antonius Deusinglaan 1
9713 AV Groningen
building 3215, 3th floor