New cellular therapies, such as CAR-T cells, CAR-NK cells, and CAR-macrophages, are in an advanced stage of development. Furthermore, hematopoietic stem cell transplantation has become one of the cornerstones of leukaemia treatment.
In addition to cellular therapies, the CRCG also focuses on targeted molecular therapy. Several small molecule inhibitors have emerged or are currently being developed. These compounds directly target mutations, downstream signalling networks, and cellular processes such as apoptosis, DNA repair, and epigenetic and metabolic changes in cancer cells.