Anaesthesiology Restoring and maintaining vital organ homeostasis Department
Patients needing emergency and perioperative care often present disruption of physiological homeostasis that can be amplified by anaesthetic and surgical interventions. Our researchers aim to better understand the underlying pathophysiology and pharmacology of these disturbances.

In our research, we use a multi-system translational approach, since ageing, disease, drugs, trauma, and surgery can interact and mutually amplify impairments in vital organs.

Our researchers focus on:

  1. The pathophysiological understanding of changes occurring during emergency unit and perioperative care, including the neurophysiological changes predisposing to chronic pain development;
  2. Quantifying and predicting these alterations using cerebral monitoring, cardiovascular measures, imaging technologies, and biomarkers;
  3. Understanding the pathophysiological consequences of drug treatments and other interventions used during and after emergency and peri-operative care;
  4. Identifying and validating new pharmacological and interventional therapeutic strategies.
  5. Finding and/or optimising therapeutic targets using advanced pharmacological modelling.
  6. Optimising clinical teaching and learning practices.

Restoring physiological homeostasis for a healthier life

Patients suffering from problems requiring procedures under anaesthetic care and/or chronic pain therapy can suffer from long-term side effects which can negatively influence healthy ageing. With our research, we want to optimally maintain or restore physiological homeostasis in these patients, thus improving their quality of life.

    1. Peri-operative pharmacology, Prof.dr. Michel MRF Struys

    2. Neuroanaesthesia and perioperative neuroscience, Prof.dr. Anthony Absalom

    3. Perioperative cardiovascular haemodynamics, Prof.dr. Thomas Scheeren

    4. Chronic and oncologic pain, Prof.dr. Andre Wolff

    5. Medical Education, Prof.dr. Götz Wietasch


Visit location in UMCG

Department of Anesthesiology (EB32)
Hanzeplein 1
9713 GZ Groningen
The Netherlands