Please visit the UMCG Research Data Catalogue for more detailed information on our data and samples.
Prior to all study visits, participants are invited to fill out a set of questionnaires on multiple topics, including socio-economic status, quality of life, physical activity, side effects of and adherence to immunosuppressive therapy, and food frequency questionnaires. At the day of the study visit, whole blood, serum, EDTA plasma, citrate plasma, heparin plasma, 24h collection urine, hair, nails and stool are collected from patients, to be stored in the TransplantLines biobank for future analyses. During study visits, included participants perform a series of physical function tests and neurocognitive tests, that provide insight into the functioning of patients, but also on the side-effects of immunosuppressive drugs, such as polyneuropathy and tremors. In addition to these samples and tests, serum, plasma and tissue samples, including e.g. samples of skin, adipose tissue, ureter, arteries, veins, trachea, explanted livers and lungs are collected. Samples are also collected at times of biopsies, e.g. at times of protocol biopsies and at times of suspected rejection.
Inclusion is ongoing, and more patients will be included in the coming years. As a result, patient numbers and available data depend on the population, time point, and specific research questions. We therefore recommend to contact us, in case you are considering using data or biomaterials collected from the TransplantLines study! Data and biomaterials can then be made available at request, after approval by the TransplantLines Research Committee.