Building improved iPSC models
The facility builds improved iPSC models and, therefore, accelerates progress in regenerative medicine. The models broaden our knowledge of the biology of iPSCs and their differentiated progeny. They also enable us to screen for modulators of their biological behaviour and to build personalized models of disease that can help physicians develop new therapeutic approaches.
Together with the Netherlands Cancer Institute and Leiden University, we serve as a national infrastructure (ScreeninC) to support targeted and genome-wide CRISPR functional screens.