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Our facility has drawn up standard protocols for proteomics analysis and offers scientific expertise in collaborative research aimed at developing new sample preparation methods, analytical techniques, and specific bioinformatics analysis approaches for proteomics and metabolomics analysis.
We support the full process of sample preparation, LC-MS analysis, and data analysis and provide expertise in experimental design, data processing and analysis, and multi-omics data integration.
The available equipment includes:
A wide range of mass spectrometers (MSs):
Sample preparation and separation systems:
Freely available and commercial data processing tools:
All MS instruments and associated equipment are operated, supported, and supervised by IMSC technicians.
Samples for MS analysis can be submitted by sending them to the IMSC facility in the ERIBA building (lab 3226.0650) or by sending an email to the IMSC email address.
Please contact us before sending samples to discuss the desired sample preparation and analysis details.
The type of service, contribution and collaboration depend on the type of research project and the input from the research group:
The general policy of the IMSC is to provide high-level mass spectrometry (MS) service to every scientist and research group from the RUG and UMCG to the best of our abilities. All MS instruments and associated equipment are operated, supported and supervised by one or more IMSC technicians, employed by RUG or UMCG. Exploitation of the IMSC, notably repair and maintenance of MS equipment, and costs of MS-specific consumables is covered by user fees. It is also used for small investments and instrument upgrades.
The personnel of IMSC together with the core partners Analytical Biochemistry (GRIP, RUG) and Pediatrics (UMCG) are continuously applying for new funds to refresh the instrument park and research infrastructure and strive to implement new analysis methods in the field of proteomics and metabolomics. The latest developments that we are working on are in the field of high throughput DIA analysis of clinical samples, glycomics and single cell proteomics.
The standard fee for internal RUG and UMCG customers was increased from 35 to 40 euro per hour (corresponding to 70-80 euros per proteomics sample) per January 1, 2023. As of September 1, 2023 we will introduce a sample-based fee system, which more accurately reflects the relative burden on our facility resources than the hours-based fee system and allows for more transparent calculations and quotations.
The fee per sample depends on the type of analysis. We distinguish the 3 main categories:
Notes:
University Medical Center Groningen (UMCG)
European Research Institute for the Biology of Ageing (ERIBA) - IMSC
PO Box 196, Internal Zip Code FA50
9700 AD Groningen
The Netherlands
Visiting address
University Medical Center Groningen (UMCG)
European Research Institute for the Biology of Ageing (ERIBA) - IMSC
Antonius Deusinglaan 1
9713 AV Groningen
location: building 3226