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The period from conception until a person’s second birthday has proven to be crucial. Many early exposures, such as nutrition, can have a long-term effect on health and development. Yet the ‘How?’ in these effects is largely unknown. How does the gut microbiome develop in babies? What is its effect? What is the effect of breast milk?
To answer these questions, the Lifelines NEXT cohort project was initiated. Lifelines NEXT is following 1,500 mother–baby pairs from pregnancy through the first years of life. Partners are invited to join the study as well. The longitudinal health data we collect will be linked to environmental factors, genetics, gut microbiome, breast milk composition and other important health parameters.
Lifelines NEXT is a cohort in the making, and we are open for collaboration!
Participants have to meet the following criteria in order to be eligible for inclusion:
Lifelines NEXT aims to include 1500 mother-baby pairs. Partners are also welcome to join Lifelines NEXT and should meet the last three inclusion criteria.
In the Research Data Catalogue you will find an overview of all biomaterials and questionnaires that is collected in Lifelines NEXT. In this overview you can see at which times biomaterials are collected and questionnaires are sent. For the content of the questionnaires, click here. An application for data is assessed by the responsible principal investigators of Lifelines NEXT.
Lifelines NEXT conducts research during pregnancy, just after childbirth and during the first years after birth (until the Lifelines NEXT children are old enough to enter the regular Lifelines study [around the age of 6-10 years]). The research consists largely of the donation of body materials; we ask for blood, faeces and (if possible) breast milk from mothers and we also take some materials from the baby.
In addition, the research consists of completing various questionnaires that, for example, deal with living situation, health, lifestyle, nutrition and the relationship between parents and their child. Next to genetic and microbiome data, this results in the collection of immune, environmental, lifestyle and health parameters over multiple time points. Until the first birthday of the child, we collect a lot of data (monthly). After that, a request will be made twice a year for completing a questionnaire and once a year for the collection of biomaterials.
Would you like to do research in Lifelines NEXT? This possibility exists. To do this, fill in either one of these forms:
Questionnaires
Medical factors
Social factors
Lifestyle
Environmental factors
Living situation
Health
Nutrition
Parent/child relationship
Biomaterials
Maternal, paternal and neonatal (cord) blood samples
Faeces (mother and child)
Vaginal swab
Placental tissue
Breast milk
Skin tapes (child)
Nasal swabs (child)
Mouth swab (child)
Urine (child)
Measurements
Bayley-III
SCORAD
Alexandra Zhernakova (Chair)
Sanne Gordijn
Menno Reijneveld
Gerard Koppelman
Jackie Dekens
Jelmer Prins
Aline Sprikkelman
Ank de Jonge
Henkjan Verkade
Jochen Mierau
Soesma Jankipersadsing
Gea Lamberts
Cobie van der Wal
Floor Pagters
Anna van der Laan
Annet Jansen
Daphne Teuben
UMCG Department Paediatrics
UMCG Department Medical sciences
For a quick introduction into Lifelines NEXT, watch: Lifelines NEXT - Aanmeldingsanimatie. For detailed information, please visit Lifelines NEXT.
Universitair Medisch Centrum Groningen
Department of Genetics
T.a.v. Lifelines NEXT
HPC:CB50
Answer number 299
9700 VB Groningen
The Netherlands
Visiting Address
Universitair Medisch Centrum Groningen
Department of Genetics
Lifelines NEXT
9700 VB Groningen
The Netherlands