The Section Molecular Genetics is interested in understanding the etiology of various complex diseases, with a specific focus on cardiovascular disease, obesity-related metabolic diseases, cancer, and ageing.

Our section aims to develop translational research between humans and mice to provide deeper insights into the complex mechanism of these diseases in humans.

We perform human studies using population- and family-based designs and generate mouse models using embryonic stem cell targeting approaches and CRISPR/Cas9 technology. These models are characterised using molecular, biochemical, histological and cellular biology techniques, proteomics, single cell genomics, and bioinformatics. The observations in mice are translated into humans using e.g. genetic validation studies.