Experimental Hematology

To deepen our insights in the development of human leukemias Department
We need to obtain detailed knowledge on (molecular) mechanisms that determine hematopoietic stem cell self-renewal and differentiation, with the ultimate goal to deepen our insights in the development of human leukemias

Our research lines

  • Mechanisms involved in HSC self-renewal and hematopoietic lineage commitment
  • Interactions between HSCs and their microenvironment
  • Molecular mechanisms underlying the development of acute myeloid leukemia
  • Role of epigenetics in normal and leukemic stem cells
  • Evaluating immunemodulatory approaches to treat hematological malignancies
  • The effects of aging on normal and leukemic stem cells
  • Hematopoietic master regulators and leukemic stem cell evolution.

Visit the hematology website