Frank Kruyt

Professor Experimental Oncology, PI Profile

Professor Experimental Oncology, PI

I am a molecular biologist and full professor of Experimental Oncology at the Department of Medical Oncology. Incomplete killing of cancer cells and the spreading of cancer cells in patients remains a major hurdle for effective therapy. My research focuses on studying the molecular basis of cancer cell invasion and survival with the aim to identify novel therapeutic targets. I am particularly interested in how the tumour microenvironment regulates adaptative responses to cellular stress and cancer cell plasticity that allow cancer cells to persist. In a multidisciplinary team different tumour types are studied, with a focus on neuro-oncological malignancies.

Discover our research

Editorial

Cancer stem cells and cellular plasticity: A preface to the special issue "Advances in understanding cancer stem cell biology and perspectives for targeted therapy"

2023, Biochemical Pharmacology

publication

Bioinspired Processing: Complex Coacervates as Versatile Inks for 3D Bioprinting

2023, Advanced materials

All publications

- Preclinical Models for Brain Tumors: Identifying Novel Therapeutic TargetsFrank Kruyt (Speaker) 20-Sep-2023 → 21-Sep-2023 Academic presentation > Academic
- Non-canonical function of the UPR sensor PERK as a regulator of cellular plasticity in glioblastomaFrank Kruyt (Speaker) 11-Sep-2023 Academic presentation > Academic
- PERK acts as a mechanotransducer in glioblastoma stem cells via regulation of the F-Actin cytoskeleton and Focal adhesion complexFrank Kruyt (Speaker) 11-May-2023 Academic presentation > Academic
- Supervision of MD/PhD student Karina KöpkeFrank Kruyt (Supervisor), Judith Paridaen (Supervisor), Inge Zuhorn (Supervisor) 1-Oct-2022 → Supervision and examination of PhD students of the UG > Academic
- Cancer in a physical context: From understanding to therapeuticsFrank Kruyt (Attendee) 29-Nov-2021 → 3-Dec-2021 Organising and contributing to an event > Academic
All activities

Frank Kruyt

Discover our research

Cancer stem cells and cellular plasticity: A preface to the special issue "Advances in understanding cancer stem cell biology and perspectives for targeted therapy"

Bioinspired Processing: Complex Coacervates as Versatile Inks for 3D Bioprinting

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Frank Kruyt

Discover our research

Cancer stem cells and cellular plasticity: A preface to the special issue "Advances in understanding cancer stem cell biology and perspectives for targeted therapy"

Bioinspired Processing: Complex Coacervates as Versatile Inks for 3D Bioprinting

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