Our research activities benefit our patients
By studying gene mutations and mechanisms of DNA damage repair, we get insight into the short-term and long-term adverse side effects of cancer treatment. These findings help us improve prognostic models and patient selection. Ultimately, we aim to better personalized treatments, increased survival rates and improved quality of life of cancer patients.
Based on our research, we identified and validated predictive and prognostic markers in several tumor types, including head-and-neck tumors, and in normal tissues. Based on these results, we improved our prediction and patient selection models, and were able to study how we can intervene with late-stage adverse effects of cancer therapies.